Treating Advanced Prostate Cancer with Diet: Part 2

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[Music] dr. Ornish and colleagues were able to show an apparent reversal in the progression of early stage localized prostate cancer with a plant-based diet and lifestyle program and researchers at the University of Massachusetts and elsewhere showed a similar diet may help slow the progression of even advanced prostate cancer or a period of four months how about six months researchers at UC San Diego found more cancer patients in the same situation put them through the same protocol these were patients who were already treated for invasive prostate cancer by either radical prostatectomy or radiation therapy yet had rising PSA levels suggesting the treatment didn’t work and the cancer was on the move in those with a cancer recurrence PSA levels typically rise exponentially reflecting the gradual inexorable growth of the cancer in the body the rate of this PSA rise is the single best predictor of the development of overt metastatic disease as well as of overall survival and the next step would be what’s called hormonal therapy which is chemical or surgical castration which has a list of side effects including loss of libido and sexual function and strength and vitality therefore we try to hold off on that for as long as possible so if we’re just waiting might as well give diet a try so they were taught to increase intake of whole grains vegetables fruit and beans and to decrease meat dairy and refined carbs of all possible lifestyle interventions why a whole food plant-based diet well if you look around the world there are huge differences in prostate cancer rates with were number one USA USA rates up to a hundred times higher than some places in Asia for example and it’s not just genetic within one generation of coming to the u.s. cancer rates shoot up and the grandkids end up with the same top of the pile rates a whole range of lifestyle factors have been looked at but diet appears to have the greatest influence specifically consumption of meat and dairy if there’s the increased risk and consumption of plant foods appears to decrease risk hence the plant-based diet a possible mechanism is arachidonic acid an inflammatory compound which we make from omega-6 rich oils like corn oil sunflower safflower and cottonseed oil and also comes preformed in animal-based foods particularly from chicken in the American diet and also eggs and then a petri dish at least arachidonic acid appears to stimulate prostate cancer cell growth as much as 200% but ask men to remove processed and animal foods from their diet for six months and what happens this is the before this is how fast their PSA levels were rising before starting the study in the absence of treatment levels of PSA tend to increase exponentially but eating healthier this happened nine of the ten patients showed an apparent slowing of cancer growth and for the nine an apparent reversal in cancer growth the average doubling time an estimate of how long it takes for their cancer to double in size slowed from doubling every year to closer to every ten years there’s been other studies using various diets and nutritional interventions like vitamin supplements but none have worked as well as this one and their compliance wasn’t even all that great they did good about boosting their whole grain consumption especially in those first three months but then back slid a bit they did eat more vegetables including a serving of greens and an extra serving of fruit at least early on at least ate one whole serving of legumes a day and they started so the researchers did observe some dietary recidivism by the end of the study the patient started out stronger but then started to slide back into old habits so the researchers checked to see if maybe they were better able to beat off the disease during that earlier period and indeed at the end of three months on average there was PSA reversal changes in the rate of PSA rise were like opposite that of whole food plant intake raising the provocative possibility that PSA may have been like tracking those changes suggesting that the adoption of a plant-based diet may have therapeutic potential in the management of recurrent prostate cancer their findings suggest that without further surgery radiation or chemo disease progression can be slowed or even reversed despite the prevailing scientific consensus that cancer progression is largely irreversible they’re not refuting the benefits of standard therapies and not guaranteeing that a plant-based diet and stress reduction will always induce remission but the results do contribute to this growing medical literature than at least some circumstances cancer may be partly reversible just by modifying dietary and lifestyle factors men may be able to prevent disease spread all without getting their testicles chopped off [Music] you

35 comments

  1. No benefit from consuming high dose vitamin C ???? – my ass

    This shows that in the dose-response analysis, an inverse linear relationship between dietary vitamin C intake and prostate cancer risk was established.

    https://www.ncbi.nlm.nih.gov/core/lw/2.0/html/tileshop_pmc/tileshop_pmc_inline.html?title=Click%20on%20image%20to%20zoom&p=PMC3&id=4532989_jcav06p0913g003.jpg

    https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4532989/

  2. Does the diet include soy milk and avoiding high methionine (an amino acid) foods? My father is in the hormone therapy (Lupron) after a brutal partial prostectomy for benign prostate enlargement. For men taking finastiride (Proscar) keep in mind that your PSA test may not be accurate, it will give you a lower score than what you actually have which can delay your cancer treatment. Our surgeon for whatever reason never asked if my father had been taking it in the past which would likely have changed the course of treatment.

  3. I wonder what are your thoughts on recent large population-based study (Mihrshani S. 2016) done in Australia that found no evidence that following a vegetarian diet has an independent protective effect on all-cause mortality? They didn't include strict vegans but one would still expect at least some positives from largely plant based diet. Anyone heard any comments on that?

  4. But egg consumption rates are really high in Japan. I'm not saying eggs are healthful, but that there's something going on in Japan. I guess the soy or (and?) green tea consumption is protective?

  5. So, now Omega 6 PUFAs increase risk for prostate cancer? I thought omega 3 and omega 6's were essential to a healthy life and many vegan foods contain both.

  6. B12 Risk. Its man made you know it isnt good. 2009 study- http://www.webmd.com/cancer/news/20091117/folic-acid-b12-may-increase-cancer-risk#1 and now 2017 study http://www.cnn.com/2017/08/22/health/vitamin-b6-b12-lung-cancer-study/index.html

  7. WHY ON EARTH WOULD ANYBODY NEED TO HAVE THEIR BALLS CHOPPED OFF – WHEN IN FACT IT IS THE HORMONE TESTOSTERONE THAT IS THE ACTUAL MOST THERAPEUTIC DURING PROSTATE ENLARGEMENT (BENIGN OR MALIGNANT)!! DON'T BELIEVE ME? WELL HOW'S THIS THEN – WHEN MEN REACH A MORE" MATURE" AGE OF AROUND 50+ WHAT HAPPENS TO THEIR TESTOSTERONE LEVELS? THEY DROP TO ABOUT HALF THAT OF WHEN IN THEIR 20'S, RIGHT? OK!! THEN, WHAT HAPPENS TO A MAN'S PROSTATE AT AROUND THAT VERY SAME AGE RANGE? IT, ON AVERAGE, ENLARGES, RIGHT? OK – SO THEREFORE – IF A MAN'S TESTOSTERONE DROP AT AGE 50+ IS DIRECTLY CORRELATED TO A MAN'S PROSTATE ENLARGEMENT AT AGE 50+ – THEN, DO THE MATH…1+1=2 – THEN WHY ON EARTH WOULD ANYBODY CHOP A MAN'S BALLS OFF AT A TIME IN HIS LIFE WHEN HE NEEDS HIS NUTS THE MOST?!!! STUPID IS AS STUPID DOES!!!

  8. Incredibly compelling information. I'm just stunned to watch prostate cancer patients eat a disgusting meat heavy diet when they give up. They just don't get it despite all the evidence being up there in lights, as bold and obvious as can be. Thank you Dr. Gregor! You are a LIFESAVER.

  9. Dr Greger! I'm 3 years vegan now and I have had many meat-eaters tell me that it's not meat that gives you disease it's the quality of it. Could this be true? I found this study and it's making me so annoyed because it might be true… I can't see if it's funded by the meat industry or not. I would love if you could look into and see if it is true…
    https://www.ncbi.nlm.nih.gov/pubmed/20479151

  10. Hey Dr Greger I need your opinion on whether face washing and moisturising from the outside is even necessary if your have a healthy diet. I heard moisturising can make your body lazy to produce moisture itself

  11. If your doubling time for PSA is 11.5 months you have a very slow growing pussy cat. Show meGleason nines with doubling time of three months. Where are larger scale studies??

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